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ATR activation is regulated by dimerization of ATR activating proteins
The checkpoint kinase ATR regulates DNA repair, cell cycle progression, and other DNA damage and replication stress responses. ATR signaling is stimulated by an ATR activating protein, and in metazoan cells, there are at least two ATR activators: TOPBP1 and ETAA1. Current evidence indicates TOPBP1 a...
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| I publikationen: | J Biol Chem |
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| Huvudupphovsmän: | , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American Society for Biochemistry and Molecular Biology
2021
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7994790/ https://ncbi.nlm.nih.gov/pubmed/33636182 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100455 |
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