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Microglial identity and inflammatory responses are controlled by the combined effects of neurons and astrocytes

Microglia, brain-resident macrophages, require instruction from the CNS microenvironment to maintain their identity and morphology and regulate inflammatory responses, although what mediates this is unclear. Here, we show that neurons and astrocytes cooperate to promote microglial ramification, indu...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Baxter, Paul S., Dando, Owen, Emelianova, Katie, He, Xin, McKay, Sean, Hardingham, Giles E., Qiu, Jing
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7994374/
https://ncbi.nlm.nih.gov/pubmed/33761343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2021.108882
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