Neurons and neuronal activity control gene expression in astrocytes to regulate their development and metabolism

The influence that neurons exert on astrocytic function is poorly understood. To investigate this, we first developed a system combining cortical neurons and astrocytes from closely related species, followed by RNA-seq and in silico species separation. This approach uncovers a wide programme of neur...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Hasel, Philip, Dando, Owen, Jiwaji, Zoeb, Baxter, Paul, Todd, Alison C., Heron, Samuel, Márkus, Nóra M., McQueen, Jamie, Hampton, David W., Torvell, Megan, Tiwari, Sachin S., McKay, Sean, Eraso-Pichot, Abel, Zorzano, Antonio, Masgrau, Roser, Galea, Elena, Chandran, Siddharthan, Wyllie, David J. A., Simpson, T. Ian, Hardingham, Giles E.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5418577/
https://ncbi.nlm.nih.gov/pubmed/28462931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15132
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