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Association Between a Tri-allelic Polymorphism in the Estrogen Metabolism Oxidoreductase NRH:Quinone Oxidoreductase 2 Gene and Risk of Breast Cancer by Molecular Subtype

Background: We hypothesized that NRH:quinone oxidoreductase 2 (NQO2) is a candidate susceptibility gene for breast cancer because of its known enzymatic activity on estrogen-derived quinones. A tri-allelic polymorphism in the NQO2 gene might be associated with the risk of luminal-like breast cancer....

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Zhou, Jiao-Qun, Zhu, Si-Yuan, He, Ye, Yu, Ke-Da
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7994273/
https://ncbi.nlm.nih.gov/pubmed/33777113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2021.658285
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