Curcumol Overcomes TRAIL Resistance of Non‐Small Cell Lung Cancer by Targeting NRH:Quinone Oxidoreductase 2 (NQO2)

Resistance to tumor‐necrosis‐factor‐related apoptosis‐inducing ligand (TRAIL) of cancer cell remains a key obstacle for clinical cancer therapies. To overcome TRAIL resistance, this study identifies curcumol as a novel safe sensitizer from a food‐source compound library, which exhibits synergistic l...

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Publicado en:Adv Sci (Weinh)
Autores principales: Zhang, Jing, Zhou, Ye, Li, Nan, Liu, Wan‐Ting, Liang, Jun‐Ze, Sun, Yue, Zhang, Wei‐Xia, Fang, Run‐Dong, Huang, Sheng‐Ling, Sun, Zheng‐Hua, Wang, Yang, He, Qing‐Yu
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7675185/
https://ncbi.nlm.nih.gov/pubmed/33240775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/advs.202002306
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