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APDL1-CART cells exhibit strong PD-L1-specific activity against leukemia cells
Chimeric antigen receptor (CAR) T cells target specific tumor antigens and lyse tumor cells in an MHC-independent manner. However, the efficacy of CAR-T cell and other cancer immunotherapies is limited by the expression of immune-checkpoint molecules such as programmed death-ligand 1 (PD-L1) on tumo...
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| Опубликовано в: : | Aging (Albany NY) |
|---|---|
| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Impact Journals
2021
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7993657/ https://ncbi.nlm.nih.gov/pubmed/33653969 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.202578 |
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