Sonidegib, a Smoothened Inhibitor, Promotes Apoptosis and Suppresses Proliferation of Natural Killer/T-Cell Lymphoma

BACKGROUND: Dysregulation of the Hedgehog (Hh) pathway modulates various aspects of hematologic and solid tumors, but its effects in human Natural killer/T-cell lymphoma (NKTCL) are unclear. Moreover, no study has examined the consequences of pharmacologically inhibiting Hh signaling in NKTCL cell l...

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Detalhes bibliográficos
Publicado no:Med Sci Monit
Main Authors: Liu, Shengquan, Li, Chuntuan, Xin, Pengliang, Zheng, Yan, Peng, Qunyi, Xu, Yahong, Luo, Ying, Wu, Yishen, Zhu, Xiongpeng
Formato: Artigo
Idioma:Inglês
Publicado em: International Scientific Literature, Inc. 2019
Assuntos:
Lab/In Vitro Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6873646/
https://ncbi.nlm.nih.gov/pubmed/31724562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.918812
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