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APDL1-CART cells exhibit strong PD-L1-specific activity against leukemia cells

Chimeric antigen receptor (CAR) T cells target specific tumor antigens and lyse tumor cells in an MHC-independent manner. However, the efficacy of CAR-T cell and other cancer immunotherapies is limited by the expression of immune-checkpoint molecules such as programmed death-ligand 1 (PD-L1) on tumo...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Aging (Albany NY)
Päätekijät: Peng, Qunyi, Zhu, Xiongpeng, Li, Chuntuan, Xin, Pengliang, Zheng, Yan, Liu, Shengquan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Impact Journals 2021
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7993657/
https://ncbi.nlm.nih.gov/pubmed/33653969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.202578
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