Implications of Polymorphisms in the BCKDK and GATA‐4 Gene Regions on Stable Warfarin Dose in African Americans

VKORC1 and CYP2C9 genotypes explain less variability in warfarin dose requirements in African Americans compared with Europeans. Variants in BCKDK and GATA‐4 gene regions, purported to regulate VKORC1 and CYP2C9 expression, have been shown to play an important role in warfarin dose requirements in E...

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Udgivet i:Clin Transl Sci
Main Authors: Bargal, Salma A., Kight, Jennifer N., Augusto de Oliveira, Felipe, Shahin, Mohamed H., Langaee, Taimour, Gong, Yan, Hamadeh, Issam S., Cooper-DeHoff, Rhonda M., Cavallari, Larisa H.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7993290/
https://ncbi.nlm.nih.gov/pubmed/33278335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12939
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