YH12852, a Potent and Selective Receptor Agonist of 5‐hydroxytryptamine, Increased Gastrointestinal Motility in Healthy Volunteers and Patients With Functional Constipation

Gastrointestinal (GI) motility disorders are common, decreases quality of life, and imposes a substantial economic burden. YH12852 is a novel agonist of 5‐hydroxytryptamine for the treatment of GI motility disorders. This phase I/IIa study assessed the tolerability, pharmacodynamic (PD) and pharmaco...

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Detalhes bibliográficos
Publicado no:Clin Transl Sci
Main Authors: Lee, Hyun A., Ju Moon, Seol, Yoo, Hyounggyoon, Kyung Kim, Mi, Bok Jang, Seong, Lee, Seoungoh, Kim, Sohee, Lee, Howard
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7993265/
https://ncbi.nlm.nih.gov/pubmed/33202093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12924
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