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Mitochondrial genotype alters the impact of rapamycin on the transcriptional response to nutrients in Drosophila

BACKGROUND: In addition to their well characterized role in cellular energy production, new evidence has revealed the involvement of mitochondria in diverse signaling pathways that regulate a broad array of cellular functions. The mitochondrial genome (mtDNA) encodes essential components of the oxid...

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Détails bibliographiques
Publié dans:BMC Genomics
Auteurs principaux: Santiago, John C., Boylan, Joan M., Lemieux, Faye A., Gruppuso, Philip A., Sanders, Jennifer A., Rand, David M.
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7992956/
https://ncbi.nlm.nih.gov/pubmed/33761878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-021-07516-2
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