FSMP-10. CYSTEINE INDUCES CYTOTOXICITY IN GLIOBLASTOMA THROUGH MITOCHONDRIAL HYDROGEN PEROXIDE PRODUCTION

Glioblastoma (GBM) is a poorly treatable disease with high mortality. Tumor metabolism in GBM is a critical mechanism responsible for growth because of upregulation of glucose, amino acid, and fatty acid utilization. However, little is known about the specific metabolic alterations in GBM that are t...

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Vydáno v:Neurooncol Adv
Hlavní autoři: Noch, Evan, Palma, Laura, Yim, Isaiah, Binder, Bhavneet, Benedetti, Elisa, Krumsiek, Jan, Elemento, Olivier, Cantley, Lewis
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2021
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7992237/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdab024.074
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