FSMP-12. A ROLE FOR PROLINE BIOSYNTHESIS IN HYPOXIC GLIOBLASTOMA

Hypoxia is a common feature of glioblastoma, and a known driver of therapy resistance in brain tumours. Understanding the metabolic adaptations to hypoxia is key to develop new effective treatments for patients. A recent screening study highlighted Pyrroline-5-carboxylate reductase-like (PYCRL) as o...

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Библиографические подробности
Опубликовано в: :Neurooncol Adv
Главные авторы: Vettore, Lisa, Westbrook, Rebecca, Roberts, Jennie, Escribano-Gonzalez, Cristina, Cuozzo, Federica, Hodson, David, Watts, Colin, Nixon, Colin, Tennant, Daniel
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2021
Предметы:
Supplement Abstracts
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7992204/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdab024.076
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