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DDRE-22. TARGETING SERINE SYNTHESIS IN BRAIN METASTASIS

The brain environment is low in amino acids, including serine and glycine, both of which are important for tumor growth as they are precursors of proteins and nucleotide bases. How tumor cells overcome these conditions to proliferate and survive in the brain is incompletely understood. Here, we show...

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Detalhes bibliográficos
Publicado no:Neurooncol Adv
Main Authors: Ngo, Bryan, Kim, Eugenie, Osorio-Vasquez, Victoria, Doll, Sophia, Bustraan, Sophia, Liang, Roger, Luengo, Alba, Davidson, Shawn, Ali, Ahmed, Ferraro, Gino, Fischer, Grant, Plasger, Ariana, Rajasekhar, Vinagolu, Kastenhuber, Edward, Eskandari, Roozbeh, Bacha, Sarah, Sriram, Roshan, Bakhoum, Samuel, Snuderl, Matija, Cotzia, Paolo, Healey, John, Sabatini, David, Jones, Drew, Zhao, Jean, Yu, Min, Jain, Rakesh, Keshari, Kayvan, Davies, Michael, Heiden, Matthew Vander, Hernando, Eva, Mann, Matthias, Cantley, Lewis, Pacold, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7992201/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdab024.044
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