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Comparative Analysis of BTK Inhibitors and Mechanisms Underlying Adverse Effects
The cytoplasmic protein-tyrosine kinase BTK plays an essential role for differentiation and survival of B-lineage cells and, hence, represents a suitable drug target. The number of BTK inhibitors (BTKis) in the clinic has increased considerably and currently amounts to at least 22. First-in-class wa...
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| Publicado en: | Front Cell Dev Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Frontiers Media S.A.
2021
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7991787/ https://ncbi.nlm.nih.gov/pubmed/33777941 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.630942 |
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