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Structure-Function Relationships of Covalent and Non-Covalent BTK Inhibitors
Low-molecular weight chemical compounds have a longstanding history as drugs. Target specificity and binding efficiency represent major obstacles for small molecules to become clinically relevant. Protein kinases are attractive cellular targets; however, they are challenging because they present one...
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| Published in: | Front Immunol |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Frontiers Media S.A.
2021
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8328433/ https://ncbi.nlm.nih.gov/pubmed/34349760 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.694853 |
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