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Significant impact of circulating tumour DNA mutations on survival in metastatic breast cancer patients

Mutational analysis of circulating tumour (ct) DNA holds promise as an effective tool to predict the course of metastatic breast cancer (MBC). In the present study we used targeted next generation sequencing of ctDNA to evaluate the impact of cancer driven mutations on the prognosis of MBC. The stud...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Muendlein, Axel, Geiger, Kathrin, Gaenger, Stella, Dechow, Tobias, Nonnenbroich, Christoph, Leiherer, Andreas, Drexel, Heinz, Gaumann, Andreas, Jagla, Wolfgang, Winder, Thomas, Mayer, Frank, Decker, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7990915/
https://ncbi.nlm.nih.gov/pubmed/33762647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-86238-7
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