Significant impact of circulating tumour DNA mutations on survival in metastatic breast cancer patients

Mutational analysis of circulating tumour (ct) DNA holds promise as an effective tool to predict the course of metastatic breast cancer (MBC). In the present study we used targeted next generation sequencing of ctDNA to evaluate the impact of cancer driven mutations on the prognosis of MBC. The stud...

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Vydáno v:Sci Rep
Hlavní autoři: Muendlein, Axel, Geiger, Kathrin, Gaenger, Stella, Dechow, Tobias, Nonnenbroich, Christoph, Leiherer, Andreas, Drexel, Heinz, Gaumann, Andreas, Jagla, Wolfgang, Winder, Thomas, Mayer, Frank, Decker, Thomas
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7990915/
https://ncbi.nlm.nih.gov/pubmed/33762647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-86238-7
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