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Hypoxia induces a HIF-1α dependent signaling cascade to make a complex metabolic switch in SGBS-adipocytes()

To elucidate the complex impact of hypoxia on adipose tissue, resulting in biased metabolism, insulin resistance and finally diabetes we used mature adipocytes derived from a Simpson-Golabi-Behmel syndrome patient for microarray analysis. We found a significantly increased transcription rate of gene...

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Bibliografiske detaljer
Main Authors: Leiherer, Andreas, Geiger, Kathrin, Muendlein, Axel, Drexel, Heinz
Format: Artigo
Sprog:Inglês
Udgivet: North Holland Publishing 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969228/
https://ncbi.nlm.nih.gov/pubmed/24275182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2013.11.009
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