Hydrogel microspheres for spatiotemporally controlled delivery of RNA and silencing gene expression within scaffold-free tissue engineered constructs

Delivery systems for controlled release of RNA interference (RNAi) molecules, including small interfering (siRNA) and microRNA (miRNA), have the potential to direct stem cell differentiation for regenerative musculoskeletal applications. To date, localized RNA delivery platforms in this area have fo...

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Detalhes bibliográficos
Publicado no:Acta Biomater
Main Authors: McMillan, Alexandra, Nguyen, Minh Khanh, Huynh, Cong Truc, Sarett, Samantha M., Ge, Peilin, Chetverikova, Melanie, Nguyen, Kien, Grosh, David, Duvall, Craig L., Alsberg, Eben
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7990721/
https://ncbi.nlm.nih.gov/pubmed/33465507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2021.01.013
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