Hydrogel microspheres for spatiotemporally controlled delivery of RNA and silencing gene expression within scaffold-free tissue engineered constructs

Delivery systems for controlled release of RNA interference (RNAi) molecules, including small interfering (siRNA) and microRNA (miRNA), have the potential to direct stem cell differentiation for regenerative musculoskeletal applications. To date, localized RNA delivery platforms in this area have fo...

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Veröffentlicht in:Acta Biomater
Hauptverfasser: McMillan, Alexandra, Nguyen, Minh Khanh, Huynh, Cong Truc, Sarett, Samantha M., Ge, Peilin, Chetverikova, Melanie, Nguyen, Kien, Grosh, David, Duvall, Craig L., Alsberg, Eben
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7990721/
https://ncbi.nlm.nih.gov/pubmed/33465507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2021.01.013
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