Cyclic Mechanical Stretch Ameliorates the Degeneration of Nucleus Pulposus Cells through Promoting the ITGA2/PI3K/AKT Signaling Pathway

BACKGROUND: Intervertebral disc degeneration (IVDD) is one of the major causes of low back pain and motor deficiency. Nucleus pulposus (NP) degeneration plays a key role in the process of IVDD. The mechanical and biological interactions involved in NP degeneration have not been elucidated. The prese...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oxid Med Cell Longev
Auteurs principaux: Wang, Dandan, Chen, Yuanzhen, Cao, Shengnan, Ren, Pengcheng, Shi, Haojun, Li, Huazhong, Xie, Liangyu, Huang, Weimin, Shi, Bin, Han, Jinxiang
Format: Artigo
Langue:Inglês
Publié: Hindawi 2021
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7990548/
https://ncbi.nlm.nih.gov/pubmed/33815660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/6699326
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