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Arginine methyltransferase PRMT5 negatively regulates cGAS-mediated antiviral immune response
Cyclic GMP-AMP synthase (cGAS) functions as an essential DNA sensor, which senses the cytoplasmic double-stranded DNA and activates the antiviral response. However, the posttranslational modification of cGAS remains to be fully understood and whether it has arginine methylation modification remains...
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| Publicado en: | Sci Adv |
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| Main Authors: | , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Association for the Advancement of Science
2021
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7990331/ https://ncbi.nlm.nih.gov/pubmed/33762328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abc1834 |
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