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TRIM50 suppressed hepatocarcinoma progression through directly targeting SNAIL for ubiquitous degradation

Tripartite motif-containing 50 (TRIM50) belongs to the tripartite motif (TRIM) protein family, which has been implicated in the pathogenesis of multiple cancers. However, the role of TRIM50 in hepatocellular carcinoma (HCC) remains to be clarified. Here we showed that TRIM50 expression was significa...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cell Death Dis
Hauptverfasser: Ma, Xiaoxiao, Ma, Xiaomin, Qiu, Yumin, Zhu, Lihui, Lin, Yueke, You, Yajing, Ma, Dapeng, Qin, Zhenzhi, Sun, Caiyu, Zhao, Yunxue, Sun, Yanlin, Han, Lihui
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5964248/
https://ncbi.nlm.nih.gov/pubmed/29789583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0644-4
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