Arginine methyltransferase PRMT5 negatively regulates cGAS-mediated antiviral immune response

Cyclic GMP-AMP synthase (cGAS) functions as an essential DNA sensor, which senses the cytoplasmic double-stranded DNA and activates the antiviral response. However, the posttranslational modification of cGAS remains to be fully understood and whether it has arginine methylation modification remains...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Ma, Dapeng, Yang, Min, Wang, Qiushi, Sun, Caiyu, Shi, Hongbiao, Jing, Weiqiang, Bi, Yuxuan, Shen, Xuecheng, Ma, Xiaomin, Qin, Zhenzhi, Lin, Yueke, Zhu, Lihui, Zhao, Yunxue, Cheng, Yeping, Han, Lihui
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2021
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7990331/
https://ncbi.nlm.nih.gov/pubmed/33762328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abc1834
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