VEGF‐C/VEGFR‐3 axis protects against pressure‐overload induced cardiac dysfunction through regulation of lymphangiogenesis

Prolonged pressure overload triggers cardiac hypertrophy and frequently leads to heart failure (HF). Vascular endothelial growth factor‐C (VEGF‐C) and its receptor VEGFR‐3 are components of the central pathway for lymphatic vessel growth (also known as lymphangiogenesis), which has crucial functions...

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Veröffentlicht in:Clin Transl Med
Hauptverfasser: Lin, Qiu‐Yue, Zhang, Yun‐Long, Bai, Jie, Liu, Jin‐Qiu, Li, Hui‐Hua
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2021
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7989711/
https://ncbi.nlm.nih.gov/pubmed/33783987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ctm2.374
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