The Ablation of VEGFR-1 Signaling Promotes Pressure Overload-Induced Cardiac Dysfunction and Sudden Death

Molecular mechanisms involved in cardiac remodelling are not fully understood. To study the role of vascular endothelial growth factor receptor 1 (VEGFR-1) signaling in left ventricular hypertrophy (LVH) and heart failure, we used a mouse model lacking the intracellular VEGFR-1 tyrosine kinase domai...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Tirronen, Annakaisa, Downes, Nicholas L., Huusko, Jenni, Laakkonen, Johanna P., Tuomainen, Tomi, Tavi, Pasi, Hedman, Marja, Ylä-Herttuala, Seppo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8002705/
https://ncbi.nlm.nih.gov/pubmed/33802976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11030452
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