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Pegylated arginine deiminase depletes plasma arginine but maintains tissue arginine availability in young pigs

Pegylated arginine deiminase (ADI-PEG20) results in the depletion of arginine with the production of isomolar amounts of citrulline. This citrulline has the potential to be utilized by the citrulline recycling pathway regenerating arginine and sustaining tissue arginine availability. The goal of thi...

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Bibliografiske detaljer
Udgivet i:Am J Physiol Endocrinol Metab
Main Authors: Mohammad, Mahmoud A., Didelija, Inka C., Stoll, Barbara, Nguyen, Trung C., Marini, Juan C.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7988784/
https://ncbi.nlm.nih.gov/pubmed/33427052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00472.2020
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