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Pegylated arginine deiminase depletes plasma arginine but maintains tissue arginine availability in young pigs

Pegylated arginine deiminase (ADI-PEG20) results in the depletion of arginine with the production of isomolar amounts of citrulline. This citrulline has the potential to be utilized by the citrulline recycling pathway regenerating arginine and sustaining tissue arginine availability. The goal of thi...

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Detalhes bibliográficos
Publicado no:Am J Physiol Endocrinol Metab
Main Authors: Mohammad, Mahmoud A., Didelija, Inka C., Stoll, Barbara, Nguyen, Trung C., Marini, Juan C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7988784/
https://ncbi.nlm.nih.gov/pubmed/33427052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00472.2020
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