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Pegylated arginine deiminase depletes plasma arginine but maintains tissue arginine availability in young pigs

Pegylated arginine deiminase (ADI-PEG20) results in the depletion of arginine with the production of isomolar amounts of citrulline. This citrulline has the potential to be utilized by the citrulline recycling pathway regenerating arginine and sustaining tissue arginine availability. The goal of thi...

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Detalles Bibliográficos
Publicado en:Am J Physiol Endocrinol Metab
Main Authors: Mohammad, Mahmoud A., Didelija, Inka C., Stoll, Barbara, Nguyen, Trung C., Marini, Juan C.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7988784/
https://ncbi.nlm.nih.gov/pubmed/33427052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00472.2020
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