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Pegylated arginine deiminase depletes plasma arginine but maintains tissue arginine availability in young pigs

Pegylated arginine deiminase (ADI-PEG20) results in the depletion of arginine with the production of isomolar amounts of citrulline. This citrulline has the potential to be utilized by the citrulline recycling pathway regenerating arginine and sustaining tissue arginine availability. The goal of thi...

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Vydáno v:Am J Physiol Endocrinol Metab
Hlavní autoři: Mohammad, Mahmoud A., Didelija, Inka C., Stoll, Barbara, Nguyen, Trung C., Marini, Juan C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7988784/
https://ncbi.nlm.nih.gov/pubmed/33427052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00472.2020
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