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Novel insights into sarcomere regulatory systems control of cardiac thin filament activation

Our review focuses on sarcomere regulatory mechanisms with a discussion of cardiac-specific modifications to the three-state model of thin filament activation from a blocked to closed to open state. We discuss modulation of these thin filament transitions by Ca(2+), by crossbridge interactions, and...

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Pubblicato in:J Gen Physiol
Autori principali: Solís, Christopher, Solaro, R. John
Natura: Artigo
Lingua:Inglês
Pubblicazione: Rockefeller University Press 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7988513/
https://ncbi.nlm.nih.gov/pubmed/33740037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.202012777
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