טוען...
Germline variants predictive of tumor mutational burden and immune checkpoint inhibitor efficacy
High tumor mutational burden (TMB) is associated with response to checkpoint blockade in several cancers. We identify pathogenic germline variants associated with increased TMB (GVITMB). GVITMB were found in 7 genes using a pan-cancer approach (APC, FANCL, SLC25A13, ERCC3, MSH6, PMS2, and TP53) and...
שמור ב:
| הוצא לאור ב: | iScience |
|---|---|
| Main Authors: | , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Elsevier
2021
|
| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7988326/ https://ncbi.nlm.nih.gov/pubmed/33786423 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2021.102248 |
| תגים: |
הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!
|