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Tumor Mutational Burden and Efficacy of Immune Checkpoint Inhibitors: A Systematic Review and Meta-Analysis

Tumor mutational burden (TMB) is a genomic biomarker that predicts favorable responses to immune checkpoint inhibitors (ICIs). Here, we set out to assess the predictive value of TMB on long-term survival outcomes in patients undergoing ICIs. We systematically searched PubMed, Embase, CENTRAL and cli...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Kim, Jong Yeob, Kronbichler, Andreas, Eisenhut, Michael, Hong, Sung Hwi, van der Vliet, Hans J., Kang, Jeonghyun, Shin, Jae Il, Gamerith, Gabriele
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6895916/
https://ncbi.nlm.nih.gov/pubmed/31731749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11111798
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