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Interaction of clinical-stage antibodies with heme predicts their physiochemical and binding qualities
Immunoglobulin repertoires contain a fraction of antibodies that recognize low molecular weight compounds, including some enzymes’ cofactors, such as heme. Here, by using a set of 113 samples with variable region sequences matching clinical-stage antibodies, we demonstrated that a considerable numbe...
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| Publicado no: | Commun Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7988133/ https://ncbi.nlm.nih.gov/pubmed/33758329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-01931-7 |
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