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Skin abnormalities in disorders with DNA repair defects, premature aging, and mitochondrial dysfunction

Defects in DNA repair pathways and alterations of mitochondrial energy metabolism have been reported in multiple skin disorders. More than ten percent of patients with primary mitochondrial dysfunction exhibit dermatological features including rashes and hair and pigmentation abnormalities. Accumula...

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Detalhes bibliográficos
Publicado no:J Invest Dermatol
Main Authors: Hussain, Mansoor, Krishnamurthy, Sudarshan, Patel, Jaimin, Kim, Edward, Baptiste, Beverly A., Croteau, Deborah L., Bohr, Vilhelm A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7987691/
https://ncbi.nlm.nih.gov/pubmed/33353663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2020.10.019
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