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Contribution of defective mitophagy to the neurodegeneration in DNA repair-deficient disorders
DNA repair is a prerequisite for life as we know it, and defects in DNA repair lead to accelerated aging. Xeroderma pigmentosum group A (XPA) is a classic DNA repair-deficient disorder with patients displaying sun sensitivity and cancer susceptibility. XPA patients also exhibit neurodegeneration, le...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Landes Bioscience
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4203523/ https://ncbi.nlm.nih.gov/pubmed/24991831 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.29321 |
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