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Contribution of defective mitophagy to the neurodegeneration in DNA repair-deficient disorders

DNA repair is a prerequisite for life as we know it, and defects in DNA repair lead to accelerated aging. Xeroderma pigmentosum group A (XPA) is a classic DNA repair-deficient disorder with patients displaying sun sensitivity and cancer susceptibility. XPA patients also exhibit neurodegeneration, le...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Scheibye-Knudsen, Morten, Fang, Evandro Fei, Croteau, Deborah L, Bohr, Vilhelm A
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Landes Bioscience 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4203523/
https://ncbi.nlm.nih.gov/pubmed/24991831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.29321
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