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DNA Damage, DNA Repair, Aging, and Neurodegeneration

Aging in mammals is accompanied by a progressive atrophy of tissues and organs, and stochastic damage accumulation to the macromolecules DNA, RNA, proteins, and lipids. The sequence of the human genome represents our genetic blueprint, and accumulating evidence suggests that loss of genomic maintena...

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Detalhes bibliográficos
Publicado no:Cold Spring Harb Perspect Med
Main Authors: Maynard, Scott, Fang, Evandro Fei, Scheibye-Knudsen, Morten, Croteau, Deborah L., Bohr, Vilhelm A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588127/
https://ncbi.nlm.nih.gov/pubmed/26385091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a025130
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