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DNA Damage, DNA Repair, Aging, and Neurodegeneration

Aging in mammals is accompanied by a progressive atrophy of tissues and organs, and stochastic damage accumulation to the macromolecules DNA, RNA, proteins, and lipids. The sequence of the human genome represents our genetic blueprint, and accumulating evidence suggests that loss of genomic maintena...

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Dettagli Bibliografici
Pubblicato in:Cold Spring Harb Perspect Med
Autori principali: Maynard, Scott, Fang, Evandro Fei, Scheibye-Knudsen, Morten, Croteau, Deborah L., Bohr, Vilhelm A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2015
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588127/
https://ncbi.nlm.nih.gov/pubmed/26385091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a025130
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