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Generation of fully functional fluorescent fusion proteins to gain insights into ABCC6 biology
ABCC6 mediates release of ATP from hepatocytes into the blood. Extracellularly, ATP is converted into the mineralization inhibitor pyrophosphate. Consequently, inactivating ABCC6 mutations give low plasma pyrophosphate underlying the ectopic mineralization disorder pseudoxanthoma elasticum. How ABCC...
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| Publicado no: | FEBS Lett |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7987643/ https://ncbi.nlm.nih.gov/pubmed/33058196 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.13957 |
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