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Generation of fully functional fluorescent fusion proteins to gain insights into ABCC6 biology
ABCC6 mediates release of ATP from hepatocytes into the blood. Extracellularly, ATP is converted into the mineralization inhibitor pyrophosphate. Consequently, inactivating ABCC6 mutations give low plasma pyrophosphate underlying the ectopic mineralization disorder pseudoxanthoma elasticum. How ABCC...
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| 出版年: | FEBS Lett |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7987643/ https://ncbi.nlm.nih.gov/pubmed/33058196 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.13957 |
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