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Homocysteine-induced decrease in HUVEC cells’ resistance to oxidative stress is mediated by Akt-dependent changes in iron metabolism

PURPOSE: Hyperhomocysteinemia is an independent risk factor for cardiovascular diseases and also promotes neuronal death in various neurodegenerative diseases. There is evidence that iron can mediate homocysteine (Hcy) toxicity. Thus, the aim of this study was to investigate the effect of Hcy on iro...

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Detalhes bibliográficos
Publicado no:Eur J Nutr
Main Authors: Borkowska, Andzelika, Ziolkowski, Wieslaw, Kaczor, Katarzyna, Herman-Antosiewicz, Anna, Knap, Narcyz, Wronska, Agata, Antosiewicz, Jedrzej
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7987610/
https://ncbi.nlm.nih.gov/pubmed/32794021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00394-020-02360-8
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