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Homocysteine-induced decrease in HUVEC cells’ resistance to oxidative stress is mediated by Akt-dependent changes in iron metabolism

PURPOSE: Hyperhomocysteinemia is an independent risk factor for cardiovascular diseases and also promotes neuronal death in various neurodegenerative diseases. There is evidence that iron can mediate homocysteine (Hcy) toxicity. Thus, the aim of this study was to investigate the effect of Hcy on iro...

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Publicat a:Eur J Nutr
Autors principals: Borkowska, Andzelika, Ziolkowski, Wieslaw, Kaczor, Katarzyna, Herman-Antosiewicz, Anna, Knap, Narcyz, Wronska, Agata, Antosiewicz, Jedrzej
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7987610/
https://ncbi.nlm.nih.gov/pubmed/32794021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00394-020-02360-8
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