hmSOD1 gene mutation‐induced disturbance in iron metabolism is mediated by impairment of Akt signalling pathway

BACKGROUND: Recently, skeletal muscle atrophy, impairment of iron metabolism, and insulin signalling have been reported in rats suffering from amyotrophic lateral sclerosis (ALS). However, the interrelationship between these changes has not been studied. We hypothesize that an impaired Akt–FOXO3a si...

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Bibliografske podrobnosti
izdano v:J Cachexia Sarcopenia Muscle
Main Authors: Halon‐Golabek, Malgorzata, Borkowska, Andzelika, Kaczor, Jan J., Ziolkowski, Wieslaw, Flis, Damian J., Knap, Narcyz, Kasperuk, Kajetan, Antosiewicz, Jedrzej
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2018
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5989766/
https://ncbi.nlm.nih.gov/pubmed/29380557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcsm.12283
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