hmSOD1 gene mutation‐induced disturbance in iron metabolism is mediated by impairment of Akt signalling pathway

BACKGROUND: Recently, skeletal muscle atrophy, impairment of iron metabolism, and insulin signalling have been reported in rats suffering from amyotrophic lateral sclerosis (ALS). However, the interrelationship between these changes has not been studied. We hypothesize that an impaired Akt–FOXO3a si...

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Vydáno v:J Cachexia Sarcopenia Muscle
Hlavní autoři: Halon‐Golabek, Malgorzata, Borkowska, Andzelika, Kaczor, Jan J., Ziolkowski, Wieslaw, Flis, Damian J., Knap, Narcyz, Kasperuk, Kajetan, Antosiewicz, Jedrzej
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2018
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5989766/
https://ncbi.nlm.nih.gov/pubmed/29380557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcsm.12283
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