Expression of the Metalloproteinase ADAM8 Is Upregulated in Liver Inflammation Models and Enhances Cytokine Release In Vitro

Acute and chronic liver inflammation is driven by cytokine and chemokine release from various cell types in the liver. Here, we report that the induction of inflammatory mediators is associated with a yet undescribed upregulation of the metalloproteinase ADAM8 in different murine hepatitis models. W...

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Vydáno v:Mediators Inflamm
Hlavní autoři: Awan, Tanzeela, Babendreyer, Aaron, Wozniak, Justyna, Alvi, Abid Mahmood, Sterzer, Viktor, Cook, Lena, Bartsch, Jörg W., Liedtke, Christian, Yildiz, Daniela, Ludwig, Andreas
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi 2021
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7987468/
https://ncbi.nlm.nih.gov/pubmed/33814981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/6665028
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