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The metalloproteinase ADAM10 requires its activity to sustain surface expression
The metalloproteinase ADAM10 critically contributes to development, inflammation, and cancer and can be controlled by endogenous or synthetic inhibitors. Here, we demonstrate for the first time that loss of proteolytic activity of ADAM10 by either inhibition or loss of function mutations induces rem...
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| Veröffentlicht in: | Cell Mol Life Sci |
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| Hauptverfasser: | , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Springer International Publishing
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7873107/ https://ncbi.nlm.nih.gov/pubmed/32372373 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-020-03507-w |
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