Expression of the Metalloproteinase ADAM8 Is Upregulated in Liver Inflammation Models and Enhances Cytokine Release In Vitro

Acute and chronic liver inflammation is driven by cytokine and chemokine release from various cell types in the liver. Here, we report that the induction of inflammatory mediators is associated with a yet undescribed upregulation of the metalloproteinase ADAM8 in different murine hepatitis models. W...

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Veröffentlicht in:Mediators Inflamm
Hauptverfasser: Awan, Tanzeela, Babendreyer, Aaron, Wozniak, Justyna, Alvi, Abid Mahmood, Sterzer, Viktor, Cook, Lena, Bartsch, Jörg W., Liedtke, Christian, Yildiz, Daniela, Ludwig, Andreas
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi 2021
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7987468/
https://ncbi.nlm.nih.gov/pubmed/33814981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/6665028
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