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Characterization of an Extensive Interface on Vitronectin for Binding to Plasminogen Activator Inhibitor-1: Adoption of Structure in an Intrinsically Disordered Region

Small-angle neutron scattering (SANS) measurements were pursued to study human vitronectin, a protein found in tissues and the circulation that regulates cell adhesion/migration and proteolytic cascades that govern hemostasis and pericellular proteolysis. Many of these functions occur via interactio...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Puster, Letitia O., Stanley, Christopher B., Uversky, Vladimir N., Curtis, Joseph E., Krueger, Susan, Chu, Yuzhuo, Peterson, Cynthia B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7987228/
https://ncbi.nlm.nih.gov/pubmed/31793295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.9b00605
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