A Mechanism for Assembly of Complexes of Vitronectin and Plasminogen Activator Inhibitor-1 from Sedimmentation Velocity Analysis

Plasminogen activator inhibitor-1 (PAI-1) and vitronectin are cofactors involved in pathological conditions such as injury, inflammation, and cancer, during which local levels of PAI-1 are increased and the active serpin forms complexes with vitronectin. These complexes become deposited into surroun...

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Главные авторы: Minor, Kenneth H., Schar, Christine R., Blouse, Grant E., Shore, Joseph D., Lawrence, Daniel A., Schuck, Peter, Peterson, Cynthia B.
Формат: Artigo
Язык:Inglês
Опубликовано: 2005
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2034521/
https://ncbi.nlm.nih.gov/pubmed/15905170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M500478200
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