Mesenchymal stem cells suppress leukemia via macrophage-mediated functional restoration of bone marrow microenvironment

Bone marrow (BM) mesenchymal stem cells (MSCs) are critical components of the BM microenvironment and play an essential role in supporting hematopoiesis. Dysfunction of MSCs is associated with the impaired BM microenvironment that promotes leukemia development. However, whether and how restoration o...

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Dettagli Bibliografici
Pubblicato in:Leukemia
Autori principali: Xia, Chengxiang, Wang, Tongjie, Cheng, Hui, Dong, Yong, Weng, Qitong, Sun, Guohuan, Zhou, Peiqing, Wang, Kaitao, Liu, Xiaofei, Geng, Yang, Ma, Shihui, Hao, Sha, Xu, Ling, Guan, Yuxian, Du, Juan, Du, Xin, Li, Yangqiu, Zhu, Xiaofan, Shi, Yufang, Xu, Sheng, Wang, Demin, Cheng, Tao, Wang, Jinyong
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7987218/
https://ncbi.nlm.nih.gov/pubmed/32094463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-020-0775-3
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