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Mesenchymal stem cells suppress leukemia via macrophage-mediated functional restoration of bone marrow microenvironment

Bone marrow (BM) mesenchymal stem cells (MSCs) are critical components of the BM microenvironment and play an essential role in supporting hematopoiesis. Dysfunction of MSCs is associated with the impaired BM microenvironment that promotes leukemia development. However, whether and how restoration o...

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Bibliografiske detaljer
Udgivet i:Leukemia
Main Authors: Xia, Chengxiang, Wang, Tongjie, Cheng, Hui, Dong, Yong, Weng, Qitong, Sun, Guohuan, Zhou, Peiqing, Wang, Kaitao, Liu, Xiaofei, Geng, Yang, Ma, Shihui, Hao, Sha, Xu, Ling, Guan, Yuxian, Du, Juan, Du, Xin, Li, Yangqiu, Zhu, Xiaofan, Shi, Yufang, Xu, Sheng, Wang, Demin, Cheng, Tao, Wang, Jinyong
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7987218/
https://ncbi.nlm.nih.gov/pubmed/32094463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-020-0775-3
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